Ternary complex crystal structure of K289M variant of DNA polymerase Beta with "hot-spot sequence" with dGTP

PDB ID: 6NKX
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2019-01-07
Classification: transcription/dna
Keywords: DNA Polymerase Beta, Conformational Change, enzyme mechanism, LFER, transcription-dna complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.98
R-value: 0.1806
Metal site idBound amino acidsBound ligands IDs
6NKX-NA-1 I1T2V1 DT P.9 HOH A.695 HOH P.205 ILE A.106 THR A.101 VAL A.103
6NKX-NA-2 C1K1L1V1 DC D.3 HOH A.593 HOH D.209 LEU A.62 LYS A.60 VAL A.65