Ternary complex crystal structure of K289M variant of DNA polymerase Beta with "hot-spot sequence" with beta-gamma CF2 analogue of dGTP

PDB ID: 6NL0
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2019-01-07
Classification: transcription/dna
Keywords: DNA Polymerase Beta, Conformational Change, enzyme mechanism, LFER, transcription-dna complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.97
R-value: 0.1928
Metal site idBound amino acidsBound ligands IDs
6NL0-NA-1 I1T2V1 DT P.9 HOH A.665 HOH P.104 ILE A.106 THR A.101 VAL A.103
6NL0-NA-2 C1K1L1V1 DC D.3 HOH A.611 HOH D.101 LEU A.62 LYS A.60 VAL A.65