Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate

PDB ID: 6P08
Gene source organism: Bacillus sp.
Expression organism: Escherichia coli-Pichia pastoris shuttle vector pPpARG4 Deposition date: 2019-05-16
Classification: TRANSFERASE/ANTIBIOTIC
Keywords: Aminoglycoside nucelotidyl transferase (ANT), Aminoglycoside modifying enzymes (AGMEs), DNA polymerase, ANTIBIOTIC, TRANSFERASE-ANTIBIOTIC complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.27
R-value: 0.1944
Metal site idBound amino acidsBound ligands IDs
6P08-MG-1 D2E1 AMP A.306 ASP A.50 ASP A.52 GLU D.145 HOH A.901 HOH A.911 HOH A.913
6P08-MG-2 D2E1 AMP A.305 ASP D.50 ASP D.52 GLU A.145 HOH D.914 HOH D.923 NMY A.307