Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493

PDB ID: 6RV3
Gene source organism: Homo sapiens
Expression organism: Spodoptera frugiperda Deposition date: 2019-05-30
Classification: MEMBRANE PROTEIN
Keywords: membrane protein, potassium channel, Structural Genomics, Structural Genomics Consortium, SGC
Technique: X-RAY DIFFRACTION
Assembly: 2
Resolution: 2.9
R-value: 0.235
Metal site idBound amino acidsBound ligands IDs
6RV3-K-1 F2G4Y2 GLY C.201 GLY C.95 GLY D.201 GLY D.95 PHE C.202 PHE D.202 TYR C.96 TYR D.96
6RV3-K-2 G4I4 GLY C.201 GLY C.95 GLY D.201 GLY D.95 ILE C.200 ILE C.94 ILE D.200 ILE D.94
6RV3-K-3 I4T4 ILE C.200 ILE C.94 ILE D.200 ILE D.94 THR C.199 THR C.93 THR D.199 THR D.93
6RV3-K-4 T4 THR C.199 THR C.93 THR D.199 THR D.93