Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site

PDB ID: 6U6B
Gene source organism: Homo sapiens
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2019-08-29
Classification: TRANSFERASE/DNA
Keywords: polymerase, cisplatin, mismatch, Pt-GG, TRANSFERASE, TRANSFERASE-DNA complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 3.1
R-value: 0.2222
Metal site idBound amino acidsBound ligands IDs
6U6B-MN-1 C1D3 ASP A.190 ASP A.192 ASP A.256 DC P.10 DZ4 A.405