Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor

PDB ID: 7DDV
Gene source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Expression organism: Mycolicibacterium smegmatis Deposition date: 2020-10-29
Classification: LYASE/LYASE INHIBITOR
Keywords: Inhibitor, LYASE, LYASE-LYASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.2
R-value: 0.1557
Metal site idBound amino acidsBound ligands IDs
7DDV-MN-1 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-2 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-3 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-4 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-5 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-6 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-7 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-8 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-9 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-10 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-11 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-12 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-13 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-14 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-15 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-16 H3 H3L A.303 HIS A.152 HIS A.177 HIS A.73
7DDV-MN-17 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-18 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-19 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-20 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-21 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-22 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-23 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-24 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-25 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-26 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-27 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-28 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-29 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-30 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-31 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-32 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-33 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-34 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-35 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-36 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-37 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-38 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-39 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74
7DDV-MN-40 H3 H3L A.303 HIS A.176 HIS A.47 HIS A.74