Crystal structure of M.tuberculosis imidazole glycerol phosphate dehydratase in complex with an inhibitor

PDB ID: 7DNQ
Gene source organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Expression organism: Mycolicibacterium smegmatis Deposition date: 2020-12-10
Classification: LYASE
Keywords: Inhibitor, LYASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.28
R-value: 0.1591
Metal site idBound amino acidsBound ligands IDs
7DNQ-MN-1 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-2 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-3 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-4 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-5 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-6 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-7 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-8 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-9 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-10 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-11 H3 GLU A.77 HOH A.407
7DNQ-MN-12 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-13 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-14 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-15 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-16 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-17 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-18 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-19 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-20 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-21 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-22 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-23 H3 GLU A.77 HOH A.407
7DNQ-MN-24 H3 HB3 A.305 HIS A.152 HIS A.177 HIS A.73
7DNQ-MN-25 H3 GLU A.180 HOH A.416
7DNQ-MN-26 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-27 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-28 H3 GLU A.180 HOH A.416
7DNQ-MN-29 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-30 H3 GLU A.180 HOH A.416
7DNQ-MN-31 H3 GLU A.180 HOH A.416
7DNQ-MN-32 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-33 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-34 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-35 H3 HB3 A.305 HIS A.176 HIS A.47 HIS A.74
7DNQ-MN-36 H3 GLU A.180 HOH A.416
7DNQ-MN-37 H3 GLU A.180 HOH A.416