Crystal structure of Isocitrate dehydrogenase D252N mutant from Trypanosoma brucei in complexed with NADP+, alpha-ketoglutarate, and ca2+

PDB ID: 7E3N
Gene source organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Expression organism: Escherichia coli Deposition date: 2021-02-09
Classification: OXIDOREDUCTASE
Keywords: TRYPANOSOMA BRUCEI, GLYCOSOME, METABOLISM, ISOCITRATE DEHYDROGENASE, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.9
R-value: 0.20528
Metal site idBound amino acidsBound ligands IDs
7E3N-CA-1 D2 ASP A.251 ASP A.274 HOH A.608 HOH A.624 HOH A.640 ICT A.503
7E3N-CA-2 D2 ASP A.251 ASP A.274 HOH A.608 HOH A.624 HOH A.640 ICT A.503