Crystal structure of KRED mutant-F147L/L153Q/Y190P/L199A/M205F/M206F and 2-hydroxyisoindoline-1,3-dione complex

PDB ID: 7EJH
Gene source organism: Lactobacillus kefiri
Expression organism: Escherichia coli 'BL21-Gold(DE3)pLysS AG' Deposition date: 2021-04-02
Classification: OXIDOREDUCTASE
Keywords: Ketoreductases, NADPH-dependent, Enantioselectivity, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.72
R-value: 0.196485901834
Metal site idBound amino acidsBound ligands IDs
7EJH-MG-1 Q2 GLN A.252 GLN B.252 HOH A.434 HOH A.516 HOH B.433 HOH B.508
7EJH-MG-2 Q2 GLN C.252 GLN D.252 HOH C.419 HOH C.538 HOH D.433 HOH D.474