Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor, di-imido triphosphate (PNPNP)

PDB ID: 7L1A
Gene source organism: Homo sapiens
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2020-12-14
Classification: TRANSFERASE/INHIBITOR
Keywords: S-adenosylmethionine, SAM synthetase, enzyme mechanism, inhibitor, TRANSFERASE-INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.25
R-value: 0.123
Metal site idBound amino acidsBound ligands IDs
7L1A-K-1 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.521 XE1 A.404
7L1A-K-2 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.521 XE1 A.404