Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P221

PDB ID: 7MTU
Gene source organism: Bacillus anthracis
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2021-05-13
Classification: OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Keywords: IMPDH, TIM barrel, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.34
R-value: 0.2312
Metal site idBound amino acidsBound ligands IDs
7MTU-K-1 C1E1G2H1S1 CYS B.308 GLU A.470 GLY B.303 GLY B.305 HIS A.472 SER A.471
7MTU-K-2 C1E1G2S1 CYS D.308 GLU B.470 GLY D.303 GLY D.305 SER B.471
7MTU-K-3 C1E1G2H1S1 CYS A.308 GLU C.470 GLY A.303 GLY A.305 HIS C.472 SER C.471
7MTU-K-4 C1E1G2S1 CYS C.308 GLU D.470 GLY C.303 GLY C.305 SER D.471