Structure of the activation intermediate of cathepsin K in complex with the 3-cyano-3-aza-beta-amino acid inhibitor Gu2602

PDB ID: 7QBM
Gene source organism: Homo sapiens
Expression organism: Komagataella phaffii GS115 Deposition date: 2021-11-19
Classification: HYDROLASE
Keywords: Cathepsin K, Protease inhibitor, Cyanohydrazide warhead, Azadipeptide nitrile, HYDROLASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.79
R-value: 0.1904
Metal site idBound amino acidsBound ligands IDs
7QBM-MG-1 S1T1 HOH A.516 HOH A.545 HOH P.538 HOH P.550 SER P.68 THR A.140