Structure of the activation intermediate of cathepsin K in complex with the azadipeptide nitrile inhibitor Gu1303

PDB ID: 7QBO
Gene source organism: Homo sapiens
Expression organism: Komagataella phaffii GS115 Deposition date: 2021-11-19
Classification: HYDROLASE
Keywords: Cathepsin K, Protease inhibitor, Cyanohydrazide warhead, Azadipeptide nitrile, HYDROLASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.9
R-value: 0.1643
Metal site idBound amino acidsBound ligands IDs
7QBO-MG-1 S1T1 HOH A.537 HOH A.584 HOH P.502 HOH P.544 SER P.68 THR A.140