Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and two sulfate in the active site

PDB ID: 7RXX
Gene source organism: Homo sapiens
Expression organism: Escherichia coli BL21(DE3) Deposition date: 2021-08-23
Classification: TRANSFERASE/TRANSFERASE INHIBITOR
Keywords: SAM SYNTHETASE, ENZYME MECHANISM, TRANSFERASE-INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.25
R-value: 0.1291
Metal site idBound amino acidsBound ligands IDs
7RXX-K-1 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.531 HOH A.571
7RXX-K-2 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.531 HOH A.571