Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction

PDB ID: 7V4F
Gene source organism: Streptomyces sp. MK730-62F2
Expression organism: Escherichia coli-Pichia pastoris shuttle vector pPpGUT1 Deposition date: 2021-08-13
Classification: ANTIBIOTIC
Keywords: caprazamycin, MraY, beta-hydroxylase, ANTIBIOTIC
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.97
R-value: 0.1911
Metal site idBound amino acidsBound ligands IDs
7V4F-FE-1 D2E2 ASP B.92 GLU B.89
7V4F-FE-2 D2 ASP A.140 ASP B.140 HOH A.336 HOH A.340 HOH B.351
7V4F-FE-3 D2 ASP A.140 ASP B.140 HOH A.336 HOH A.340 HOH B.351