Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with S-adenosylmethionine, adenosin and diphosphono-aminophosphonic acid.

PDB ID: 8AXZ
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2022-09-01
Classification: TRANSFERASE
Keywords: methionine adenosyltransferase, SAM-producing metabolic enzyme, cancer target, TRANSFERASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 1.1
R-value: 0.1676
Metal site idBound amino acidsBound ligands IDs
8AXZ-K-1 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.593 PPK A.401
8AXZ-K-2 A1D1E1 ALA A.259 ASP A.258 GLU A.57 HOH A.593 PPK A.401