Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg

PDB ID: 8GRD
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2022-09-01
Classification: OXIDOREDUCTASE
Keywords: Isocitrate dehydrogenase, NAD-dependent IDH, assembly, allosteric regulation, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.699
R-value: 0.194
Metal site idBound amino acidsBound ligands IDs
8GRD-MG-1 D3 ASP A.230 ASP A.234 ASP B.217 HOH B.522