Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca

PDB ID: 8GRU
Gene source organism: Homo sapiens
Expression organism: Escherichia coli Deposition date: 2022-09-02
Classification: OXIDOREDUCTASE
Keywords: Isocitrate dehydrogenase, NAD-dependent IDH, assembly, allosteric regulation, OXIDOREDUCTASE
Technique: X-RAY DIFFRACTION
Assembly: 1
Resolution: 2.847
R-value: 0.2084
Metal site idBound amino acidsBound ligands IDs
8GRU-CA-1 D2 ASP A.230 ASP B.217