Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates
PDB ID:4I0Z Metal site ID: 4I0Z-ZN-2 Bound amino acids or nucleotide residues: D1E1 Group identifier: D1K1S1 Is homomeric: True Amino acid or nucleotide residue IDs: ASP A.167 GLU A.165 All ligands IDs: ASP A.167 GLU A.165 Number of coordinating amino acids or nucleotide residues: 2 Number of coordinating ligands: 2 Number of coordinating chains: 2 Number of coordinating chains: 2
Representative metal site in the group:4I0Z-ZN-1 Similar binding_sites: