Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1

PDB ID: 5OI2
Metal site ID: 5OI2-MG-2
Bound amino acids or nucleotide residues: Q1Y1
Group identifier: E1K1Q1T1V1
Is homomeric: True
Amino acid or nucleotide residue IDs: GLN A.177 TYR A.99
All ligands IDs: HOH A.434 ILE A.84
Number of coordinating amino acids or nucleotide residues: 2
Number of coordinating ligands: 2
Number of coordinating chains: 2
Number of coordinating chains: 2
Representative metal site in the group: 5OI2-MG-1
Similar binding_sites:
Metal site idBound amino acidsBound ligands IDs
5OI2-MG-2Q1Y1 HOH A.434 ILE A.84