Novel Modes of Inhibition of Wild-Type IDH1:Direct Covalent Modification of His315 with Cmpd11

PDB ID: 6BL0
Metal site ID: 6BL0-MG-2
Bound amino acids or nucleotide residues: D2
Group identifier: K1R2
Is homomeric: True
Amino acid or nucleotide residue IDs: ASP C.252 ASP C.275
All ligands IDs: ASP C.252 ASP C.275 HOH C.606 HOH C.632 ICT C.501
Number of coordinating amino acids or nucleotide residues: 2
Number of coordinating ligands: 5
Number of coordinating chains: 2
Number of coordinating chains: 2
Representative metal site in the group: 6BL0-MG-1
Similar binding_sites:
Metal site idBound amino acidsBound ligands IDs
5H3E-MG-1D2 ASP A.314 ASP B.291 ICT A.502
6BL0-MG-2D2 ASP C.252 ASP C.275 HOH C.606 HOH C.632 ICT C.501
6PAY-MG-1D2 ASP B.275 ASP C.252 ICT B.501