Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
PDB ID:7PIU Metal site ID: 7PIU-CA-1 Bound amino acids or nucleotide residues: D1X1 Group identifier: C1D2E1H1X1 Is homomeric: False Amino acid or nucleotide residue IDs: ASP R.126 DPN P.5 All ligands IDs: ASP R.126 DPN P.5 Number of coordinating amino acids or nucleotide residues: 2 Number of coordinating ligands: 2 Number of coordinating chains: 2 Number of coordinating chains: 2