Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate
PDB ID:7PJM Metal site ID: 7PJM-CA-2 Bound amino acids or nucleotide residues: D3 Group identifier: K1R1V1 Is homomeric: True Amino acid or nucleotide residue IDs: ASP A.252 ASP B.275 ASP B.279 All ligands IDs: AKG B.502 ASP A.252 ASP B.275 ASP B.279 HOH B.611 HOH B.637 Number of coordinating amino acids or nucleotide residues: 3 Number of coordinating ligands: 6 Number of coordinating chains: 2 Number of coordinating chains: 2
Representative metal site in the group:3INM-CA-1 Similar binding_sites: