| 6NGK |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.83 |
0.1905 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGN |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.9 |
0.2003 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGM |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.69 |
0.1831 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGB |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
1.9 |
0.1771 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGF |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
1.99 |
0.1855 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NG8 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
1.9 |
0.1879 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NG2 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
1.93 |
0.1773 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NG1 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
2.15 |
0.2044 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NG4 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
1.776 |
0.1778 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NHC |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
12/21/2018 |
2.16 |
0.1846 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NHE |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE |
12/21/2018 |
1.999 |
0.1852 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGZ |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
2.0 |
0.1987 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NH0 |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.898 |
0.1881 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGQ |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.95 |
0.1938 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGS |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.9 |
0.1802 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGV |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
1.829 |
0.1857 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6NGU |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine |
oxidoreductase/oxidoreductase inhibitor |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex |
12/21/2018 |
2.0 |
0.2151 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 2J83 |
Ulilysin metalloprotease in complex with batimastat. |
HYDROLASE |
HYDROLASE, IGFBP PROTEASE, METALLOPROTEASE, HYDROXAMATE INHIBITOR, CANCER, METZINCIN |
10/18/2006 |
2.0 |
0.161 |
METHANOSARCINA ACETIVORANS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 2KIK |
An artificial di-iron oxo-protein with phenol oxidase activity |
DE NOVO PROTEIN |
diiron proteins, four-heix bundle, de novo design, oxidase, DE NOVO PROTEIN |
05/06/2009 |
— |
— |
— |
— |
SOLUTION NMR |
— |
| 9NSE |
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, ETHYL-ISOSELENOUREA COMPLEX |
OXIDOREDUCTASE |
NITRIC OXIDE SYNTHASE, HEME PROTEIN, TETRAHYDROBIOPTERIN, OXIDOREDUCTASE |
01/13/1999 |
2.2 |
0.197 |
Bos taurus |
Escherichia coli BL21 |
X-RAY DIFFRACTION |
1 |