| 4Q45 |
DNA Polymerase- damaged DNA complex |
TRANSFERASE/DNA |
POLYMERASE, DNA POLYMERASE, DNA, TRANSFERASE-DNA COMPLEX |
04/13/2014 |
2.176 |
0.2118 |
Escherichia coli |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4R17 |
Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome |
HYDROLASE/HYDROLASE INHIBITOR |
Proteasome, Drug Development, Binding Analysis, Umpolung, Crosslink, HYDROLASE-HYDROLASE INHIBITOR complex |
08/04/2014 |
2.1 |
0.185 |
Saccharomyces cerevisiae S288c |
— |
X-RAY DIFFRACTION |
1 |
| 4R65 |
Ternary complex crystal structure of R258A mutant of DNA polymerase Beta |
Transferase/DNA |
DNA Polymerase Beta, Conformational Change, enzyme mechanism, Transferase-DNA complex |
08/22/2014 |
1.95 |
0.1869 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4QV1 |
yCP beta5-M45A mutant |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/14/2014 |
2.5 |
0.19425 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV3 |
yCP beta5-M45V mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
3.0 |
0.17141 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV4 |
yCP beta5-M45T mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.7 |
0.18966 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV5 |
yCP beta5-M45I mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.7 |
0.18878 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV7 |
yCP beta5-A50V mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.6 |
0.18811 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV8 |
yCP beta5-C52F mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.9 |
0.19195 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV0 |
yCP beta5-A49T-A50V-double mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
3.1 |
0.15936 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4R82 |
Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 in complex with NAD and FAD fragments |
OXIDOREDUCTASE |
structural genomics, PSI-Biology, protein structure initiative, Midwest Center for Structural Genomics, MCSG, Enzyme Discovery for Natural Product Biosynthesis, NatPro, OXIDOREDUCTASE |
08/29/2014 |
1.66 |
0.1631 |
Streptomyces globisporus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4QW4 |
yCP in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/16/2014 |
2.8 |
0.18716 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QW5 |
yCP beta5-M45A mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/16/2014 |
3.0 |
0.1693 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QW6 |
yCP beta5-M45V mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/16/2014 |
2.9 |
0.17689 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QW7 |
yCP beta5-M45T mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/16/2014 |
2.7 |
0.20495 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QV9 |
yCP beta5-C63F mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.6 |
0.19616 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QUY |
yCP beta5-A49S-mutant |
HYDROLASE |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE |
07/14/2014 |
2.8 |
0.19102 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QWR |
yCP beta5-C52F mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/17/2014 |
2.9 |
0.18061 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QWS |
yCP beta5-C63F mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/17/2014 |
3.0 |
0.17449 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |
| 4QWJ |
yCP beta5-A49T-mutant in complex with carfilzomib |
HYDROLASE/HYDROLASE INHIBITOR |
Cancer, Proteasome, Bortezomib, Drug Resistance, Binding Analysis, HYDROLASE-HYDROLASE INHIBITOR complex |
07/16/2014 |
2.9 |
0.191 |
Saccharomyces cerevisiae |
SACCHAROMYCES CEREVISIAE |
X-RAY DIFFRACTION |
1 |