| 7M44 |
DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 90 sec |
REPLICATION |
Time-Lapse Crystallography, DNA Polymerase Lambda, Double Strand Break Repair, DNA Synthesis Fidelity, REPLICATION |
03/21/2021 |
1.9 |
0.1949 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7M47 |
DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 60 min |
REPLICATION |
Time-Lapse Crystallography, DNA Polymerase Lambda, Double Strand Break Repair, DNA Synthesis Fidelity, REPLICATION |
03/21/2021 |
1.648 |
0.1797 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7M46 |
DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 5 min |
REPLICATION |
Time-Lapse Crystallography, DNA Polymerase Lambda, Double Strand Break Repair, DNA Synthesis Fidelity, REPLICATION |
03/21/2021 |
1.92 |
0.1862 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7M48 |
DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 960 min |
REPLICATION |
Time-Lapse Crystallography, DNA Polymerase Lambda, Double Strand Break Repair, DNA Synthesis Fidelity, REPLICATION |
03/21/2021 |
1.93 |
0.1839 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7M2V |
Crystallographic Structure of the Rhombohedral Crystal Form of STMV Grown from Chloride |
VIRUS/RNA |
VIRUS-RNA complex |
03/17/2021 |
1.8 |
0.2054 |
Satellite tobacco mosaic virus |
— |
X-RAY DIFFRACTION |
1 |
| 7M0A |
Incomplete in crystallo incorporation by DNA Polymerase Lambda bound to blunt-ended DSB substrate and incoming dTTP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
1.83 |
0.169 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7M0C |
Post-catalytic nicked complex of DNA Polymerase Lambda with bound mismatched DSB substrate |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
2.65 |
0.1804 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7M0B |
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound mismatched DSB and incoming dUMPNPP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
2.0 |
0.1705 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7M0D |
Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound complementary DSB substrate and incoming dUMPNPP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
1.8 |
0.1643 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7LMZ |
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 1) |
TRANSLOCASE |
p97, NMS-873, single-particle cryo-EM, translocation, allosteric inhibition, TRANSLOCASE |
02/06/2021 |
— |
— |
Homo sapiens |
Escherichia coli K-12 |
ELECTRON MICROSCOPY |
1 |
| 7M07 |
Pre-catalytic ternary complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
1.57 |
0.1705 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7M09 |
Pre-catalytic quaternary complex of DNA Polymerase Lambda with blunt-ended DSB substrate and incoming dUMPNPP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
1.65 |
0.1677 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7M08 |
Post-catalytic nicked complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP |
TRANSFERASE |
Nonhomologous end-joining, Base Excision Repair, TRANSFERASE |
03/10/2021 |
1.7 |
0.1855 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7LN2 |
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 1) |
TRANSLOCASE |
p97, NMS-873, single-particle cryo-EM, translocation, allosteric inhibition, TRANSLOCASE |
02/06/2021 |
— |
— |
Homo sapiens |
Escherichia coli |
ELECTRON MICROSCOPY |
1 |
| 7LAT |
Campylobacter jejuni keto-acid reductoisomerase in complex with Mg2+ |
ISOMERASE |
metalloenzyme, reductoisomerase, ISOMERASE |
01/06/2021 |
2.47 |
0.1588 |
Campylobacter jejuni |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7KTE |
DNA Polymerase Mu, 8-oxodGTP:Ct Reaction State Ternary Complex, 50 mM Mg2+ (90min) |
REPLICATION |
Time-Lapse Crystallography, Oxidized Nucleotide Insertion, DNA Polymerase Mu, Double Strand Break Repair, REPLICATION |
11/24/2020 |
1.479 |
0.1568 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7KTG |
DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mg2+ (960min) |
REPLICATION |
Time-Lapse Crystallography, Oxidized Nucleotide Insertion, DNA Polymerase Mu, Double Strand Break Repair, REPLICATION |
11/24/2020 |
1.445 |
0.1577 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7KTF |
DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mg2+ (180min) |
REPLICATION |
Time-Lapse Crystallography, Oxidized Nucleotide Insertion, DNA Polymerase Mu, Double Strand Break Repair, REPLICATION |
11/24/2020 |
1.489 |
0.1674 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7KTN |
DNA Polymerase Mu, 8-oxodGTP:At Product State Ternary Complex, 10 mM Mg2+ (2160min) |
REPLICATION |
Time-Lapse Crystallography, Oxidized Nucleotide Insertion, DNA Polymerase Mu, Double Strand Break Repair, REPLICATION |
11/24/2020 |
1.33 |
0.1414 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7KTH |
DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 10 mM Mg2+ (2160min) |
REPLICATION |
Time-Lapse Crystallography, Oxidized Nucleotide Insertion, DNA Polymerase Mu, Double Strand Break Repair, REPLICATION |
11/24/2020 |
1.476 |
0.1663 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |