| 7UAN |
Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with (6-(3-(4,4-difluoropiperidin-1-yl)propyl)-4-methylpyridin-2-amine) |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
03/13/2022 |
1.6969 |
0.2224 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7UAM |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (6-(3-(4,4-difluoropiperidin-1-yl)propyl)-4-methylpyridin-2-amine) |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
03/13/2022 |
1.837 |
0.1704 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
2 |
| 7TS7 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(methylamino)propyl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.9 |
0.1896 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
2 |
| 7TS6 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.8 |
0.1795 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS9 |
Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with 6-(3-(dimethylamino)propyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.8526 |
0.2301 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS8 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-chloro-6-((5-(2-(dimethylamino)ethyl)-2,3-difluorophenyl)ethynyl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
2.3 |
0.2191 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
2 |
| 7TSC |
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)propyl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.1796 |
0.2109 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TSB |
Structure of rat neuronal nitric oxide synthase R349A heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.8177 |
0.2135 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TSE |
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)propyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.75 |
0.2154 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TSD |
Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.769 |
0.2223 |
Rattus norvegicus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7TSA |
Structure of rat neuronal nitric oxide synthase R349A/H692F mutant heme domain in complex with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
2.03 |
0.2338 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TSF |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(4,4-difluoropiperidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.776 |
0.1811 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS3 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
2.099 |
0.2013 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS2 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)propyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.9758 |
0.1819 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS5 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.84 |
0.213 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS4 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)prop-1-yn-1-yl)pyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
1.85 |
0.1778 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TS1 |
Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(4,4-difluoropiperidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE |
nitric oxide synthase inhibitor, heme enzyme, OXIDOREDUCTASE |
01/31/2022 |
2.06 |
0.202 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7TGH |
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila |
MEMBRANE PROTEIN |
Mitochondrial respiration, Electron transport chain, Oxidoreductase, Super-complex CI+III2, Membrane protein |
01/07/2022 |
— |
— |
Tetrahymena thermophila |
— |
ELECTRON MICROSCOPY |
1 |
| 7SPZ |
Nucleotide-free Get3 in two open forms |
CHAPERONE |
Tail-anchored membrane protein targeting Deviant Walker A ATPase targeting factor, CHAPERONE |
11/04/2021 |
2.77 |
0.29314 |
Giardia lamblia ATCC 50803 |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7SP0 |
Crystal structure of human SFPQ L534I mutant in complex with zinc |
RNA BINDING PROTEIN |
SFPQ, DBHS PROTEIN, RRM, ZN, POLYMERIZATION, NUCLEAR PROTEIN, ALS mutation, RNA BINDING PROTEIN |
11/01/2021 |
1.83 |
0.1785 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |