7U1Q |
Cryo-EM structure of the pancreatic ATP-sensitive potassium channel bound to ATP and repaglinide with SUR1-in conformation |
MEMBRANE PROTEIN |
KATP channel, SUR1, Kir6.2, repaglinide, RPG, sulfonylurea receptor, potassium transport, MEMBRANE PROTEIN |
02/21/2022 |
— |
— |
Rattus norvegicus |
Rattus norvegicus |
ELECTRON MICROSCOPY |
1 |
7KZ0 |
Human MBD4 glycosylase domain bound to DNA containing substrate analog 2'-deoxy-pseudouridine |
HYDROLASE/DNA |
MBD4, protein-DNA complex, HYDROLASE-DNA complex |
12/09/2020 |
1.57 |
0.1883 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
7TDL |
M379A mutant tyrosine phenol-lyase complexed with 3-bromo-DL-phenylalanine |
LYASE |
pyridoxal-5'-phosphate, mutation, substrate specificity, LYASE |
01/01/2022 |
1.6 |
0.1774 |
Citrobacter freundii |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
7SK1 |
TWIK1 in MSP1E3D1 Lipid Nanodisc at pH 5.5 |
TRANSPORT PROTEIN |
K+ Channel, pH, TRANSPORT PROTEIN |
10/19/2021 |
— |
— |
Rattus norvegicus |
Komagataella pastoris |
ELECTRON MICROSCOPY |
1 |
7JZ7 |
Dihydrodipicolinate synthase mutant S48F |
LYASE |
enzyme, Dihydrodipicolinate synthase, LYASE |
09/01/2020 |
1.74 |
0.14905 |
Escherichia coli |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
7JZ9 |
Dihydrodipicolinate synthase S48F with pyruvate and succinic semi-aldehyde |
LYASE |
Enzyme, Allostery, lysine biosynthesis, DHDPS, Substrate complex, LYASE |
09/01/2020 |
1.82 |
0.14318 |
Escherichia coli |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
7JZF |
Dihydrodipicolinate synthase mutant S48F with pyruvate in the catalytic site |
LYASE |
Enzyme, DHDPS, Allostery, Ligand, Lysine Biosynthesis, LYASE |
09/02/2020 |
1.82 |
0.14431 |
Escherichia coli |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
7SJ1 |
Structure of shaker-W434F |
MEMBRANE PROTEIN |
potassium channel, MEMBRANE PROTEIN |
10/15/2021 |
— |
— |
Drosophila melanogaster |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
7AU6 |
Cytochrome c oxidase structure in O-state |
MEMBRANE PROTEIN |
Terminal oxidase Cytochrome c oxidase aa3 oxidase, MEMBRANE PROTEIN |
11/02/2020 |
— |
— |
Paracoccus denitrificans |
— |
ELECTRON MICROSCOPY |
1 |
7B6C |
BK Polyomavirus VP1 pentamer fusion with long C-terminal extended arm |
VIRAL PROTEIN |
Viral protein, Polyomavirus, Capsid protein, chimera |
12/07/2020 |
2.48 |
0.205 |
BK polyomavirus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
2 |
8DVP |
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine |
HYDROLASE/DNA |
Protein-DNA complex, DNA repair, Base Excision Repair, HYDROLASE, HYDROLASE-DNA complex |
07/29/2022 |
1.54 |
0.2172 |
Geobacillus stearothermophilus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
8DVY |
DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate |
HYDROLASE/DNA |
Protein-DNA complex, DNA repair, Apurinic/Apyrimidinic, Base Excision Repair, HYDROLASE, HYDROLASE-DNA complex |
07/30/2022 |
2.36 |
0.2474 |
Geobacillus stearothermophilus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
4ZKP |
P22 Tail Needle Gp26 crystallized at pH 7.0 |
VIRAL PROTEIN |
Viral protein, P22, Tail Needle, Membrane penetration |
04/30/2015 |
2.1 |
0.154 |
Enterobacteria phage P22 |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
8E57 |
Rabbit L-type voltage-gated calcium channel Cav1.1 in the presence of Amiodarone and 100 microM MNI-1 at 2.8 Angstrom resolution |
TRANSPORT PROTEIN |
Cav1.1, Channels, Calcium Ion-Selective, TRANSPORT PROTEIN |
08/20/2022 |
— |
— |
Oryctolagus cuniculus |
— |
ELECTRON MICROSCOPY |
1 |
8E59 |
Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone at 3.1 Angstrom resolution |
TRANSPORT PROTEIN |
Cav1.3, Channels, Calcium Ion-Selective, TRANSPORT PROTEIN |
08/20/2022 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
8E5B |
Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone and Sofosbuvir at 3.3 Angstrom resolution |
TRANSPORT PROTEIN |
Cav1.3, Channels, Calcium Ion-Selective, TRANSPORT PROTEIN |
08/20/2022 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
7B0D |
Sugar transaminase from Archaeoglobus veneficus |
TRANSFERASE |
aminotransferase, thermostability, catalysis, TRANSFERASE |
11/19/2020 |
1.27 |
0.1516 |
Archaeoglobus veneficus (strain DSM 11195 / SNP6) |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
8D1J |
hBest1 5mM Ca2+ (Ca2+-bound) closed state |
TRANSPORT PROTEIN |
Ion channel, chloride channel, anion channel, pentamer, TRANSPORT PROTEIN |
05/27/2022 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
8D1I |
hBest1 1uM Ca2+ (Ca2+-bound) closed state |
TRANSPORT PROTEIN |
Ion channel, chloride channel, anion channel, pentamer, TRANSPORT PROTEIN |
05/27/2022 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
8D1L |
hBest1 Ca2+-bound partially open aperture state |
TRANSPORT PROTEIN |
Ion channel, chloride channel, anion channel, pentamer, TRANSPORT PROTEIN |
05/27/2022 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |