| 6CR6 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH-CH3, beta, gamma dATP analogue |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
03/16/2018 |
2.1 |
0.2161 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR5 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH2-beta, gamma dATP analogue |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, Acidity modification, TRANSFERASE-DNA complex |
03/16/2018 |
1.98 |
0.1778 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR8 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (R & S isomers), beta, gamma dATP analogue |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
03/16/2018 |
2.05 |
0.1906 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR7 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHF, beta, gamma dATP analogue |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
03/16/2018 |
2.29 |
0.1738 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR9 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CFCL, beta, gamma dATP analogue |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
03/16/2018 |
1.96 |
0.1797 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR4 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with dATP |
TRANSFERASE/DNA |
Conformational Change, enzyme mechanism, LFER, Acidity Modification, TRANSFERASE-DNA complex |
03/16/2018 |
1.8 |
0.173 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6CR3 |
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CBr2, beta, gamma dATP analogue |
transcription/DNA |
DNA Polymerase Beta, Conformational Change, enzyme mechanism, LFER, transcription-DNA complex |
03/16/2018 |
1.95 |
0.1748 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BDA |
Wild-type I-OnuI bound to A3G substrate (post-cleavage complex) |
HYDROLASE/DNA |
Nucleic Acid, HYDROLASE, HYDROLASE-DNA complex |
10/22/2017 |
1.88 |
0.1911 |
Ophiostoma novo-ulmi subsp. americana |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BEL |
Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP |
TRANSFERASE/DNA |
DNA Polymerase Beta, Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
10/25/2017 |
1.88 |
0.1678 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BEM |
Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP |
TRANSFERASE/DNA |
DNA Polymerase Beta, Conformational Change, enzyme mechanism, LFER, TRANSFERASE-DNA complex |
10/25/2017 |
1.88 |
0.187 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BKY |
Novel Binding Modes of Inhibition of Wild-Type IDH1: Allosteric Inhibition with Cmpd2 |
OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor |
dehydrogenase, inhibitor, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex |
11/09/2017 |
2.17 |
0.185 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BL0 |
Novel Modes of Inhibition of Wild-Type IDH1:Direct Covalent Modification of His315 with Cmpd11 |
OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor |
dehydrogenase, inhibitor, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex |
11/09/2017 |
2.165 |
0.196 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 6C07 |
Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum |
TRANSFERASE |
S-Adenosylmethionine synthetase, Enzyme metabolism, Anti-infective target, Anti-cancer target, TRANSFERASE |
12/28/2017 |
1.85 |
0.1573 |
Cryptosporidium parvum (strain Iowa II) |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6BRX |
Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion |
REPLICATION |
Cisplatin, DNA adduct, translesion DNA synthesis, polymerase kappa, chemoresistance, REPLICATION |
12/01/2017 |
2.8 |
0.21359 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6C3O |
Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form |
TRANSPORT PROTEIN |
ATP-dependent potassium channel Kir6.2 SUR1 ATP ADP, TRANSPORT PROTEIN |
01/10/2018 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
| 6BS1 |
Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion |
REPLICATION |
Cisplatin, DNA adduct, translesion DNA synthesis, polymerase kappa, chemoresistance, REPLICATION |
12/01/2017 |
3.15 |
0.2442 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6BTF |
DNA Polymerase Beta I260Q Ternary Complex |
TRANSFERASE,LYASE/DNA |
Lyase, DNA complex, TRANSFERASE, LYASE-DNA complex |
12/06/2017 |
1.75 |
0.1749 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6C6Q |
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor |
VIRAL PROTEIN/LIPID BINDING PROTEIN |
Norovirus, Capsid protein, Protruding domain, Ig-V like, VIRAL PROTEIN-LIPID BINDING PROTEIN complex, CD300lf, VP1, myeloid receptor, CMRF-35-like molecule-1, CLM-1, CLM1, DIR2, IREM1, LMIR3, PIGR3, IgSF13 |
01/19/2018 |
2.0 |
0.182 |
Murine norovirus 1 |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 4WB2 |
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a complement anaphylatoxin |
DNA-RNA HYBRID |
protein-RNA complex, mirror-image aptamer, G-quadruplex, complement anaphylatoxin, DNA-RNA hybrid |
09/02/2014 |
1.8 |
0.167 |
Mus musculus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4WB3 |
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin |
DNA-RNA HYBRID |
protein-RNA complex, mirror-image aptamer, G-quadruplex, complement anaphylatoxin, DNA-RNA hybrid |
09/02/2014 |
2.0 |
0.1626 |
Mus musculus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |