| 2PQK |
X-ray crystal structure of human Mcl-1 in complex with Bim BH3 |
APOPTOSIS |
Bcl-2 family, BH3 domain, APOPTOSIS |
05/02/2007 |
2.0 |
0.194 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
3 |
| 2PCU |
Human carboxypeptidase A4 in complex with a cleaved hexapeptide. |
HYDROLASE |
metallocarboxypeptidase; metalloprotease; product; cleavage; specificity; human carboxypeptidase A4, HYDROLASE |
03/30/2007 |
1.6 |
0.159 |
Homo sapiens |
Pichia pastoris |
X-RAY DIFFRACTION |
1 |
| 2PDO |
Crystal Structure of the Putative Acetyltransferase of GNAT Family from Shigella flexneri |
TRANSFERASE |
alpha-beta-alpha sandwich, Structural Genomics, PSI-2, Protein Structure Initiative, Midwest Center for Structural Genomics, MCSG, TRANSFERASE |
04/01/2007 |
2.0 |
0.193 |
Shigella flexneri 2a |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
5 |
| 2PH1 |
Crystal structure of nucleotide-binding protein AF2382 from Archaeoglobus fulgidus, Northeast Structural Genomics Target GR165 |
LIGAND BINDING PROTEIN |
alpha-beta protein, Structural Genomics, PSI-2, Protein Structure Initiative, Northeast Structural Genomics Consortium, NESG, LIGAND BINDING PROTEIN |
04/10/2007 |
2.7 |
0.217 |
Archaeoglobus fulgidus DSM 4304 |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2NL9 |
Crystal structure of the Mcl-1:Bim BH3 complex |
APOPTOSIS |
Apoptosis, Bcl-2, Mcl-1, Bim |
10/19/2006 |
1.5 |
0.173 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 2NQJ |
Crystal structure of Escherichia coli endonuclease IV (Endo IV) E261Q mutant bound to damaged DNA |
HYDROLASE |
Tim_barrel, trinuclear zinc site, HYDROLASE |
10/31/2006 |
2.45 |
0.198 |
Escherichia coli |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 2NQ9 |
High resolution crystal structure of Escherichia coli endonuclease IV (Endo IV) Y72A mutant bound to damaged DNA |
HYDROLASE/DNA |
TIM-barrel, trinuclear Zn active site, HYDROLASE-DNA COMPLEX |
10/30/2006 |
1.41 |
0.22 |
Escherichia coli |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2O3K |
Yeast Cytosine Deaminase D92E Triple Mutant bound to transition state analogue HPY |
HYDROLASE |
Homodimer, Transition State Analogue, HYDROLASE |
12/01/2006 |
2.3 |
0.204 |
Saccharomyces cerevisiae |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2O3Z |
X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate |
HYDROLASE |
Lipid A biosynthesis, Lipid synthesis, LpxC, 3-heptyloxybenzoate, HYDROLASE |
12/02/2006 |
2.25 |
0.197 |
Aquifex aeolicus |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 2O6D |
Structure of native rTp34 from Treponema pallidum |
MEMBRANE PROTEIN, PROTEIN BINDING |
Ig-fold, syphilis, metal-ion binding, dimer, MEMBRANE PROTEIN, PROTEIN BINDING |
12/07/2006 |
1.86 |
0.188 |
Treponema pallidum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2NVV |
Crystal Structure of the Putative Acetyl-CoA hydrolase/transferase PG1013 from Porphyromonas gingivalis, Northeast Structural Genomics Target PgR16. |
HYDROLASE |
alpha beta protein, Structural Genomics, PSI-2, Protein Structure Initiative, Northeast Structural Genomics Consortium, NESG, HYDROLASE |
11/13/2006 |
2.7 |
0.287 |
Porphyromonas gingivalis |
Escherichia coli |
X-RAY DIFFRACTION |
3 |
| 2O8M |
Crystal structure of the S139A mutant of Hepatitis C Virus NS3/4A protease |
VIRAL PROTEIN |
SERINE PROTEASE, NS3, NS4A, HEPATITIS C VIRUS, Viral Protein |
12/12/2006 |
2.0 |
0.194 |
Hepatitis C virus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2OM1 |
Structure of human insulin in presence of thiocyanate at pH 6.5 |
HORMONE |
R6 conformation, hormone |
01/20/2007 |
1.97 |
0.17463 |
Homo sapiens |
— |
X-RAY DIFFRACTION |
3 |
| 2OLZ |
Structure of human insulin in presence of thiocyanate at pH 7.0 |
HORMONE |
R6 conformation, hormone |
01/20/2007 |
1.7 |
0.1784 |
Homo sapiens |
— |
X-RAY DIFFRACTION |
1 |
| 2MGT |
Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's disease pathogenic English mutation H6R |
PROTEIN FIBRIL, METAL BINDING PROTEIN |
Alzheimer's disease, Human amyloid -peptide, Zinc binding, PROTEIN FIBRIL, METAL BINDING PROTEIN |
11/06/2013 |
— |
— |
Homo sapiens |
— |
SOLUTION NMR |
1 |
| 2HX4 |
Rat nNOS heme domain complexed with 4-N-(Nw-nitro-L-argininyl)-trans-4-hydroxyamino-L-proline amide |
OXIDOREDUCTASE |
nitric oxide synthase, heme enzyme, inhibitor, OXIDOREDUCTASE |
08/02/2006 |
2.15 |
0.203 |
Rattus norvegicus |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 2HZC |
Crystal structure of the N-terminal RRM of the U2AF large subunit |
RNA BINDING PROTEIN |
RNA splicing, RRM, RNA recognition, alternative conformation, RNA BINDING PROTEIN |
08/08/2006 |
1.47 |
0.139 |
Homo sapiens |
Escherichia coli BL21 |
X-RAY DIFFRACTION |
2 |
| 2IER |
Crystal Structure of Aquifex aeolicus LpxC Complexed with Uridine 5'-Diphosphate |
HYDROLASE |
alpha + beta fold, HYDROLASE |
09/19/2006 |
2.7 |
0.213 |
Aquifex aeolicus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2IMT |
The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site |
APOPTOSIS |
dimer, APOPTOSIS |
10/04/2006 |
1.48 |
0.1925 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 2IMS |
The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site |
APOPTOSIS |
dimer, APOPTOSIS |
10/04/2006 |
1.47 |
0.17925 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |