4M1C |
Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40) |
HYDROLASE |
hydrolase, Zinc metalloprotease |
08/02/2013 |
3.5 |
0.2278 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
4LUX |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine |
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR |
nitric oxide synthase, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex |
07/25/2013 |
1.86 |
0.17996 |
Rattus norvegicus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
4LCZ |
Crystal structure of a multilayer-packed major light-harvesting complex |
MEMBRANE PROTEIN |
Light collecting, Photon protection, Grana stacking, Chlorophyll binding, MEMBRANE PROTEIN |
06/24/2013 |
2.6 |
0.25 |
Spinacia oleracea |
— |
X-RAY DIFFRACTION |
1 |
4LEP |
Structural insights into substrate recognition in proton dependent oligopeptide transporters |
membrane protein, tranport protein |
MFS superfamily, Peptide transporter, membrane protein, tranport protein |
06/26/2013 |
3.2 |
0.2748 |
Shewanella oneidensis |
Escherichia coli |
X-RAY DIFFRACTION |
3 |
4LJQ |
Crystal structure of the catalytic core of E3 ligase HOIP |
LIGASE |
RNF31, ZIBRA, RING domain, Zinc finger, IBR domain, RBR ligase, E3 ligase, Ligase, Ubiquitin, HOIL-1, Sharpin |
07/05/2013 |
2.45 |
0.2065 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
5 |
4KS6 |
Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 166-174 stretch |
HYDROLASE/HYDROLASE INHIBITOR |
Clostridial neurotoxin zinc protease, Peptidase_M27, SNAP 25, covalent inhibition, HYDROLASE-HYDROLASE INHIBITOR complex |
05/17/2013 |
1.79 |
0.19255 |
Clostridium botulinum A |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
4L3K |
Crystal structure of Sporosarcina pasteurii UreE bound to Ni2+ and Zn2+ |
CHAPERONE |
ferredoxin-like motif, urease accessory protein, metal binding, chaperone |
06/06/2013 |
1.88 |
0.17076 |
Sporosarcina pasteurii |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
4KTX |
Crystal structure of the catalytic domain of botulinum neurotoxin BoNT/A C134S mutant with covalent inhibitor that modifies Cys-165 causing disorder in 167-174 stretch |
HYDROLASE/HYDROLASE INHIBITOR |
Clostridial neurotoxin zinc protease, Peptidase_M27, SNAP 25, covalent inhibition, HYDROLASE-HYDROLASE INHIBITOR complex |
05/21/2013 |
2.59 |
0.202 |
Clostridium botulinum A |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
2V9F |
L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT E192A- K248W-A273S) |
LYASE |
ENTROPY INDEX, METAL-BINDING, OLIGOMERIZATION, ZINC, LYASE, ALDOLASE, CLASS II, CYTOPLASM, CLEAVAGE OF L-RHAMNULOSE-1-PHOSPHATE TO DIHYDROXYACETONEPH BACTERIAL L-RHAMNOSE METABOLISM, INTERFACE DESIGN, SURFACE MUTATION, 2-KETOSE DEGRADATION, PROTEIN-PROTEIN INTERFACE, RARE SUGAR, AGGREGATION, ZINC ENZYME, FIBRILLATION, RHAMNOSE METABOLISM, PROTEIN ENGINEERING |
08/23/2007 |
2.1 |
0.185 |
ESCHERICHIA COLI |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
3BOO |
Structure of the C. botulinum neurotoxin serotype A with an inhibitory peptide bound |
TOXIN/TOXIN INHIBITOR |
botulinum, neurotoxin, metalloprotease, peptidic inhibitor, TOXIN-TOXIN INHIBITOR COMPLEX |
12/17/2007 |
1.4 |
0.148 |
Clostridium botulinum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
3C8A |
Crystal structure of the catalytic domain of botulinum neurotoxin serotype A with inhibitory peptide RRGL |
HYDROLASE/HYDROLASE INHIBITOR |
BOTULINUM NEUROTOXIN TYPE A, CATALYTIC DOMAIN, ENDOPEPTIDASE, BIO-WARFARE AGENT, METALLOPROTEASE, PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR complex |
02/11/2008 |
1.52 |
0.192 |
Clostridium botulinum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
3C8B |
Crystal structure of the catalytic domain of botulinum neurotoxin serotype A with inhibitory peptide RRGI |
HYDROLASE/HYDROLASE INHIBITOR |
BOTULINUM NEUROTOXIN TYPE A, CATALYTIC DOMAIN, ENDOPEPTIDASE, BIO-WARFARE AGENT, METALLOPROTEASE, PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR complex |
02/11/2008 |
1.47 |
0.204 |
Clostridium botulinum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
3BVX |
GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with Methyl (2-deoxy-2-acetamido-beta-D-glucopyranosyl)-(1->2)-(alpha-D-mannopyranosyl)- (1->3)-[(alpha-D-mannopyranosyl)-(1->6)-(alpha-D-mannopyranosyl)-(1->6)]-beta-D-mannopyranoside |
HYDROLASE |
FAMILY 38 GLYCOYSL HYDROLASE, Glycosidase, Golgi apparatus, Membrane, Signal-anchor, Transmembrane, HYDROLASE |
01/07/2008 |
1.1 |
0.153 |
Drosophila melanogaster |
Drosophila melanogaster |
X-RAY DIFFRACTION |
1 |
3C89 |
Crystal structure of the catalytic domain of botulinum neurotoxin serotype A with inhibitory peptide RRGM |
HYDROLASE/HYDROLASE INHIBITOR |
BOTULINUM NEUROTOXIN TYPE A, CATALYTIC DOMAIN, ENDOPEPTIDASE, BIO-WARFARE AGENT, METALLOPROTEASE, PROTEASE, SECRETED, HYDROLASE-HYDROLASE INHIBITOR complex |
02/11/2008 |
1.58 |
0.196 |
Clostridium botulinum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
4A47 |
Crosstalk between Cu(I) and Zn(II) homeostasis |
TRANSPORT PROTEIN |
TRANSPORT PROTEIN, METAL-TRANSPORTING ATPASES |
10/07/2011 |
1.9 |
0.19466 |
SYNECHOCYSTIS SP. |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |
4AA1 |
Crystal structure of ANCE in complex with Angiotensin-II |
HYDROLASE/HORMONE |
HYDROLASE-HORMONE COMPLEX, HYDROLASE, SUBSTRATE BINDING |
11/30/2011 |
1.99 |
0.18835 |
HOMO SAPIENS |
PICHIA PASTORIS |
X-RAY DIFFRACTION |
1 |
4AD9 |
Crystal structure of human LACTB2. |
HYDROLASE |
HYDROLASE, METALLO-BETA LACTAMASE, MITOCHONDRIA |
12/22/2011 |
2.6 |
0.1775 |
HOMO SAPIENS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |
4ASQ |
Crystal structure of ANCE in complex with Bradykinin |
HYDROLASE |
HYDROLASE, ZINC METALLOPROTEASE, SUBSTRATE RECOGNITION |
05/02/2012 |
1.97 |
0.18035 |
DROSOPHILA MELANOGASTER |
KOMAGATAELLA PASTORIS |
X-RAY DIFFRACTION |
1 |
4ASR |
Crystal structure of ANCE in complex with Thr6-Bradykinin |
HYDROLASE |
HYDROLASE, ZINC METALLOPROTEASE, SUBSTRATE RECOGNITION |
05/02/2012 |
1.9 |
0.18274 |
DROSOPHILA MELANOGASTER |
KOMAGATAELLA PASTORIS |
X-RAY DIFFRACTION |
1 |
4ATY |
Crystal structure of a Terephthalate 1,2-cis-dihydrodioldehydrogenase from Burkholderia xenovorans LB400 |
OXIDOREDUCTASE |
OXIDOREDUCTASE |
05/11/2012 |
1.85 |
0.21049 |
BURKHOLDERIA XENOVORANS LB400 |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |