| 7BYN |
Cryo-EM structure of human KCNQ4 with linopirdine |
MEMBRANE PROTEIN |
KCNQ, Channel, Calmodulin, PIP2, linopirdine, MEMBRANE PROTEIN |
04/23/2020 |
— |
— |
Aequorea victoria |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
| 7CN0 |
Cryo-EM structure of K+-bound hERG channel |
TRANSPORT PROTEIN |
potassium channel, TRANSPORT PROTEIN |
07/29/2020 |
— |
— |
Homo sapiens |
Homo sapiens |
ELECTRON MICROSCOPY |
1 |
| 7CO6 |
Binary complex of DNA polymerase Mu with 1-nt gapped DNA (templating thymine) |
HYDROLASE/DNA |
polymerase mu, misincorporation, gap filling, mutagenesis, HYDROLASE, HYDROLASE-DNA complex |
08/04/2020 |
1.9 |
0.1796 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 6YEI |
Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD |
OXIDOREDUCTASE |
glutamate dehydrogenase, 2-oxoglutarate, NAD, amino acid metabolism, OXIDOREDUCTASE |
03/24/2020 |
2.02 |
0.1604 |
Arabidopsis thaliana |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6YEH |
Arabidopsis thaliana glutamate dehydrogenase isoform 1 in apo form |
OXIDOREDUCTASE |
glutamate dehydrogenase, 2-oxoglutarate, NAD, amino acid metabolism, OXIDOREDUCTASE |
03/24/2020 |
2.59 |
0.1827 |
Arabidopsis thaliana |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 6I9D |
MloK1 consensus structure from single particle analysis of 2D crystals |
MEMBRANE PROTEIN |
Voltage-gated potassium channel, Cyclic nucleotide-binding domain, ion channel, ion transport, MEMBRANE PROTEIN |
11/23/2018 |
— |
— |
Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) |
Escherichia coli BL21(DE3) |
ELECTRON MICROSCOPY |
1 |
| 6CF1 |
Proteus vulgaris HigA antitoxin structure |
ANTITOXIN |
Helix-turn-helix motif, transcriptional regulator, toxin-antitoxin, ANTITOXIN |
02/13/2018 |
1.9 |
0.1804 |
Proteus vulgaris |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 1NZM |
NMR structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 complexed with the telomerase inhibitor RHPS4 |
DNA |
Quadruplex DNA, telomeres, telomerase inhibition, NMR spectroscopy, molecular dynamics, drug-DNA interaction, TTAGGGT REPEAT, DNA |
02/18/2003 |
— |
— |
— |
— |
SOLUTION NMR |
— |
| 1JPQ |
Crystal Structure of the Oxytricha Telomeric DNA at 1.6A |
DNA |
Oxytricha, G-Quartets, DNA |
08/03/2001 |
1.6 |
0.225 |
— |
— |
X-RAY DIFFRACTION |
1 |
| 1JR1 |
Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid |
OXIDOREDUCTASE |
DEHYDROGENASE, IMPD, IMPDH, GUANINE NUCLEOTIDE SYNTHESIS, MYCOPHENOLIC ACID, MPA, OXIDOREDUCTASE |
08/09/2001 |
2.6 |
0.217 |
Cricetulus griseus |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 1JRN |
Orthorhombic form of Oxytricha telomeric DNA at 2.0A |
DNA |
oxytricha, G-quartets, DNA |
08/14/2001 |
2.0 |
0.2183 |
— |
— |
X-RAY DIFFRACTION |
1 |
| 1NF7 |
Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide |
OXIDOREDUCTASE |
8 STRANDED PARALLE ALPHA/BETA BARREL, DEHYDROGENASE, IMPD, IMPDH, RIBAVIRIN MONOPHOSPHATE, C2-MAD, OXIDOREDUCTASE |
12/13/2002 |
2.65 |
0.238 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 1NKI |
CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND PHOSPHONOFORMATE |
TRANSFERASE |
POTASSIUM BINDING LOOP, MANGANESE BINDING, TRANSFERASE |
01/03/2003 |
0.95 |
0.147 |
Pseudomonas aeruginosa |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 1TGY |
Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate |
TRANSFERASE |
uridine phosphorylase, pyrimidine nucleoside phosphorylase, uridine salvage, uridine, TRANSFERASE |
05/31/2004 |
2.2 |
0.16 |
Escherichia coli |
Escherichia coli K12 |
X-RAY DIFFRACTION |
1 |
| 1V3P |
Crystal structure of d(GCGAGAGC): the DNA octaplex structure with I-motif of G-quartet |
DNA |
octaplex, quadruplex, G-quartet, I-motif, I-motif of G-quartet, base-intercalated duplex, base-intercalated motif, sheared G:A pair, DNA, deoxyribonucleic acid, X-ray analysis |
11/03/2003 |
2.3 |
0.234 |
— |
— |
X-RAY DIFFRACTION |
1 |
| 1V3O |
Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex |
DNA |
octaplex, quadruplex, G-duet, base-intercalated duplex, base-intercalated motif, sheared G:A pair, DNA, deoxyribonucleic acid, X-ray analysis |
11/03/2003 |
1.7 |
0.262 |
— |
— |
X-RAY DIFFRACTION |
1 |
| 1V3N |
Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex |
DNA |
octaplex, quadruplex, G-duet, base-intercalated duplex, base-intercalated motif, sheared G:A pair, DNA, deoxyribonucleic acid, X-ray analysis, crystal struture |
11/03/2003 |
1.8 |
0.225 |
— |
— |
X-RAY DIFFRACTION |
1 |
| 1W19 |
Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate |
TRANSFERASE |
TRANSFERASE, RIBOFLAVIN BIOSYNTHESIS, LUMAZINE SYNTHASE, INHIBITOR BINDING |
06/03/2004 |
2.0 |
0.149 |
MYCOBACTERIUM TUBERCULOSIS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 1W29 |
Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)butane 1-phosphate |
TRANSFERASE |
TRANSFERASE, RIBOFLAVIN BIOSYNTHESIS, LUMAZINE SYNTHASE, INHIBITOR BINDING |
07/01/2004 |
2.3 |
0.174 |
MYCOBACTERIUM TUBERCULOSIS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 1PVN |
The crystal structure of the complex between IMP dehydrogenase catalytic domain and a transition state analogue MZP |
OXIDOREDUCTASE |
Transition state analogue, IMP dehydrogenase, Mizoribine 5'-monophosphate, distal flap, general base, drug selectivity, OXIDOREDUCTASE |
06/27/2003 |
2.0 |
0.196 |
Tritrichomonas foetus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |