| 7RTW |
Cryo-EM structure of a TTYH3 cis-dimer |
MEMBRANE PROTEIN |
TTYH2, momomer, MEMBRANE PROTEIN |
08/15/2021 |
— |
— |
Mus musculus |
Mammalia |
ELECTRON MICROSCOPY |
1 |
| 7RTT |
Cryo-EM structure of a TTYH2 cis-dimer |
MEMBRANE PROTEIN |
TTYH2, Cisdimer, MEMBRANE PROTEIN |
08/15/2021 |
— |
— |
Mus musculus |
Mammalia |
ELECTRON MICROSCOPY |
1 |
| 7RBH |
Human DNA polymerase beta crosslinked ternary complex 2 |
TRANSFERASE/DNA |
protein-DNA crosslink, polymerase, lyase, dRP, TRANSFERASE, TRANSFERASE-DNA complex |
07/06/2021 |
1.75 |
0.1793 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7RCD |
Second stage reengineered variant of I-OnuI targeting human PD1 gene with activity enhancing substitutions |
DNA BINDING PROTEIN/DNA |
meganuclease, gene editing, protein engineering, DNA BINDING PROTEIN-DNA complex |
07/07/2021 |
2.448 |
0.2354 |
Synthetic construct |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7RCC |
First stage engineered variant of I-OnuI after initial reassembly |
DNA BINDING PROTEIN/DNA |
meganuclease, gene editing, protein engineering, DNA BINDING PROTEIN-DNA complex |
07/07/2021 |
2.45 |
0.2219 |
Synthetic construct |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7RAC |
Crystal structure of a dodecameric multicopper oxidase from M. hydrothermalis in an orthorhombic lattice |
OXIDOREDUCTASE |
multicopper oxidase thermophile dodecamer laccase, OXIDOREDUCTASE |
06/30/2021 |
2.36 |
0.1386 |
Marinithermus hydrothermalis |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7QZR |
Structure of native leukocyte myeloperoxidase in complex with the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus |
OXIDOREDUCTASE |
Phagocytosis Innate Immune Response Inhibitor Complex, OXIDOREDUCTASE |
01/31/2022 |
2.18 |
0.2038 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 7R5Z |
Monocot chimeric jacalin JAC1 from Oryza sativa: dirigent domain (crystal form 1) |
PLANT PROTEIN |
Monocot chimeric jacalin, Dirigent protein, Lectin, Pathogen resistance, PLANT PROTEIN |
02/12/2022 |
1.75 |
0.191 |
Oryza sativa |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7QHM |
Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (stigmatellin and azide bound) |
OXIDOREDUCTASE |
supercomplex, respiratory chain, cytochrome bcc-aa3 supercomplex, proton translocation, bioenergetics, membrane protein, electron transport, OXIDOREDUCTASE |
12/13/2021 |
— |
— |
Corynebacterium glutamicum ATCC 13032 |
Corynebacterium glutamicum ATCC 13032 |
ELECTRON MICROSCOPY |
1 |
| 7QB5 |
Coxsackievirus A24v (CVA24v) in complex with a dimeric C2-C9-linked sialic acid inhibitor |
VIRUS |
Coxsackievirus A24v, CVA24v, sialic acid based inhibitor, VIRUS |
11/18/2021 |
1.728 |
0.1656 |
Coxsackievirus A24 |
Homo sapiens |
X-RAY DIFFRACTION |
1 |
| 7PSY |
X-ray crystal structure of perdeuterated LecB lectin in complex with perdeuterated fucose |
SUGAR BINDING PROTEIN |
lectin, complex, SUGAR BINDING PROTEIN |
09/24/2021 |
0.9 |
0.1158 |
Pseudomonas aeruginosa |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7PRG |
Joint X-ray/neutron room temperature structure of perdeuterated LecB lectin in complex with perdeuterated fucose |
SUGAR BINDING PROTEIN |
lectin, complex, SUGAR BINDING PROTEIN |
09/21/2021 |
1.9 |
0.1042 |
Pseudomonas aeruginosa |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7PIU |
Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution. |
SIGNALING PROTEIN |
GPCR, MELANOCORTIN-4 RECEPTOR, MELANOCORTIN RECEPTORS, SETMELANOTIDE, NDP-ALPHA-MSH, ALPHA-MSH, ANTAGONISM, AGONISM, APPETITE REGULATION, ANTI-OBESITY TREATMENT, SIGNALING PROTEIN |
08/23/2021 |
— |
— |
Homo sapiens |
Spodoptera aff. frugiperda 1 BOLD-2017 |
ELECTRON MICROSCOPY |
1 |
| 7PIV |
Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution. |
SIGNALING PROTEIN |
GPCR, MELANOCORTIN-4 RECEPTOR, MELANOCORTIN RECEPTORS, SETMELANOTIDE, NDP-ALPHA-MSH, ALPHA-18 MSH, ANTAGONISM, AGONISM, APPETITE REGULATION, ANTI-OBESITY TREATMENT, SIGNALING PROTEIN |
08/23/2021 |
— |
— |
Homo sapiens |
Spodoptera frugiperda |
ELECTRON MICROSCOPY |
1 |
| 7PJM |
Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and Ca2+/2-Oxoglutarate |
OXIDOREDUCTASE |
OXIDOREDUCTASE |
08/24/2021 |
2.1 |
0.1805 |
Homo sapiens |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 7PHW |
PfCyRPA bound to monoclonal antibody Cy.004 Fab fragment |
IMMUNE SYSTEM |
malaria, Plasmodium falciparum, monoclonal antibody, vaccine, IMMUNE SYSTEM |
08/18/2021 |
2.79 |
0.2391 |
Plasmodium falciparum (isolate 3D7) |
Homo sapiens |
X-RAY DIFFRACTION |
1 |
| 7OJ7 |
Crystal structure of human coxsackievirus A24v in complex with a pentavalent N-acetylneuraminic acid conjugate |
VIRUS |
human Coxsackievirus A24v, starfish-like inhibitor, corannulene, VIRUS |
05/14/2021 |
1.78 |
0.1577 |
Coxsackievirus A24 |
Homo sapiens |
X-RAY DIFFRACTION |
1 |
| 7NP8 |
Crystal structure of the Coenzyme F420-dependent sulfite reductase from Methanocaldococcus jannaschii at 2.3-A resolution |
OXIDOREDUCTASE |
Sulfite detoxification, Sulfur metabolism, sulfide, hydrogenotrophic methanogens, iron-sulfur cluster, sulfite-reductase evolution, sulfite/nitrite reductase, siroheme, flavin, oxidoreductase, ferredoxin, F420, hyperthermophile |
02/26/2021 |
2.299 |
0.1817 |
Methanocaldococcus jannaschii DSM 2661 |
— |
X-RAY DIFFRACTION |
2 |
| 7NI3 |
CRYSTAL STRUCTURE OF NATIVE HUMAN MYELOPEROXIDASE IN COMPLEX WITH CPD 3 |
OXIDOREDUCTASE |
OXIDOREDUCTASE, COMPLEX, INHIBITOR |
02/11/2021 |
2.1 |
0.175 |
Homo sapiens |
— |
X-RAY DIFFRACTION |
1 |
| 7NI1 |
CRYSTAL STRUCTURE OF NATIVE HUMAN MYELOPEROXIDASE IN COMPLEX WITH CPD 9 |
OXIDOREDUCTASE |
OXIDOREDUCTASE, COMPLEX, INHIBITOR |
02/11/2021 |
2.1 |
0.217 |
Homo sapiens |
— |
X-RAY DIFFRACTION |
1 |