| 2XE0 |
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus |
DNA BINDING PROTEIN/DNA |
DNA BINDING PROTEIN-DNA COMPLEX, HOMING ENDONUCLEASES, DOUBLE-STRAND BREAK, HOMOLOGOUS RECOMBINATION, HUMAN RAG1 GENE, SEVERE COMBINED IMMUNODEFICIENCY (SCID), DNA BINDING PROTEIN |
05/10/2010 |
2.31 |
0.2131 |
CHLAMYDOMONAS REINHARDTII |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 2XMA |
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE RIGHT END DNA COMPLEX |
DNA BINDING PROTEIN/DNA |
DNA BINDING PROTEIN-DNA COMPLEX, TRANSPOSITION, MOBILE ELEMENT |
07/26/2010 |
2.3 |
0.2152 |
DEINOCOCCUS RADIODURANS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 2XM3 |
Deinococcus radiodurans ISDra2 Transposase Left end DNA complex |
DNA BINDING PROTEIN/DNA |
DNA BINDING PROTEIN-DNA COMPLEX, TRANSPOSITION, MOBILE ELEMENT |
07/22/2010 |
2.3 |
0.2179 |
DEINOCOCCUS RADIODURANS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |
| 3T80 |
Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine |
LYASE |
IspF, Isoprenoid biosynthesis, SSGCID, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, Alpha Beta, LYASE |
07/31/2011 |
2.5 |
0.211 |
Salmonella enterica subsp. enterica serovar Typhimurium |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 3SZ5 |
Crystal Structure of LHK-Exo in complex with 5-phosphorylated oligothymidine (dT)4 |
HYDROLASE/DNA |
alkaline exonuclease, digest double stranded DNA, strict 5-3-polarity, HYDROLASE-DNA complex |
07/18/2011 |
2.8 |
0.19342 |
Laribacter hongkongensis |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3TCX |
Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation |
CELL ADHESION |
Rossmann Fold, Immunoglobulin-Like Fold, Cell Adhesion, Membrane |
08/09/2011 |
3.6 |
0.21762 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
5 |
| 3TFR |
Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CF2)PP in the active site |
TRANSFERASE/DNA |
DNA Polymerase, stereoselectivity, TRANSFERASE-DNA complex |
08/16/2011 |
2.0 |
0.1876 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3TFS |
Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer |
TRANSFERASE/DNA |
stereoselectivity, DNA Polymerase, TRANSFERASE-DNA complex |
08/16/2011 |
2.0 |
0.1876 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3TNQ |
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme |
TRANSFERASE |
PKA RIIb tetrameric holoenzyme, TRANSFERASE |
09/01/2011 |
3.097 |
0.2313 |
Rattus norvegicus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3U6F |
Mouse TREX1 D200N mutant |
HYDROLASE/DNA |
RNase H fold, 3' exonuclease, HYDROLASE-DNA complex |
10/12/2011 |
2.3 |
0.2193 |
Mus musculus |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3L4P |
Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]- |
OXIDOREDUCTASE |
Molybdenum-containing enzymes, Aldehyde oxidoreductase, Xanthine oxidase family, Reduced form, Arsenite inhibition, 2Fe-2S, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Molybdenum, NAD, Oxidoreductase |
12/21/2009 |
1.45 |
0.142 |
Desulfovibrio gigas |
— |
X-RAY DIFFRACTION |
2 |
| 3KSA |
Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (cleaved form) |
ISOMERASE/DNA |
Topoisomerase, protein-DNA cleavage complex, Streptococcus pneumoniae, DNA-binding, nucleotide-binding, quinolone, Cleaved form, ISOMERASE-DNA COMPLEX |
11/21/2009 |
3.3 |
0.1762 |
Streptococcus pneumoniae |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3KSB |
Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (re-sealed form) |
ISOMERASE/DNA |
Topoisomerase, protein-DNA cleavage complex, Streptococcus pneumoniae, DNA-binding, nucleotide-binding, quinolone, Sealed DNA form, ISOMERASE-DNA COMPLEX |
11/21/2009 |
3.5 |
0.1813 |
Streptococcus pneumoniae |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3KYL |
Structure of the catalytic subunit of telomerase bound to its RNA template and telomeric DNA |
NUCLEIC ACID BINDING PROTEIN/DNA/RNA |
Reverse Transcriptase, Protein-RNA-DNA complex, TELOMERASE, RNA-directed DNA polymerase, NUCLEIC ACID BINDING PROTEIN-DNA-RNA complex |
12/06/2009 |
2.7 |
0.24234 |
Tribolium castaneum |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3LD0 |
Crystal structure of B.licheniformis Anti-TRAP protein, an antagonist of TRAP-RNA interactions |
GENE REGULATION |
Anti-TRAP, AT, TRAP, tryptophan RNA-binding attenuation protein, transcription attenuation, antitermination, transcription factors, tryptophan biosynthesis regulation, GENE REGULATION |
01/12/2010 |
2.2 |
0.19383 |
Bacillus licheniformis |
Escherichia coli |
X-RAY DIFFRACTION |
3 |
| 3LK9 |
DNA polymerase beta with a gapped DNA substrate and dTMP(CF2)P(CF2)P |
Lyase,Transferase/DNA |
Nucleotidyl Transferase, DNA Polyemrase, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Lyase, Magnesium, Metal-binding, Methylation, Nucleotidyltransferase, Nucleus, Transferase, Transferase-DNA complex |
01/27/2010 |
2.5 |
0.198 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3GAH |
Structure of a F112H variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP |
TRANSFERASE |
TRANSFERASE |
02/17/2009 |
1.17 |
0.16 |
Lactobacillus reuteri |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3GAI |
Structure of a F112A variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP |
TRANSFERASE |
TRANSFERASE |
02/17/2009 |
1.48 |
0.156 |
Lactobacillus reuteri |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3GAJ |
Structure of a C-terminal deletion variant of a PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP |
TRANSFERASE |
TRANSFERASE |
02/17/2009 |
1.38 |
0.164 |
Lactobacillus reuteri |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 3GDX |
Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP |
TRANSFERASE/DNA |
NUCLOETIDYL TRANSFERASE, DNA POLYMERASE, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Lyase, Magnesium, Metal-binding, Nucleotidyltransferase, Nucleus, Polymorphism, Sodium, Transferase, TRANSFERASE-DNA COMPLEX |
02/24/2009 |
2.2 |
0.208 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |