| 4CHG |
Crystal structure of VapBC15 complex from Mycobacterium tuberculosis |
TOXIN/ANTITOXIN |
TOXIN-ANTITOXIN COMPLEX, PIN DOMAIN |
12/02/2013 |
2.1 |
0.1674 |
MYCOBACTERIUM TUBERCULOSIS |
Escherichia coli BL21(DE3) |
X-RAY DIFFRACTION |
1 |
| 4DHQ |
Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening |
PROTEIN BINDING/INHIBITOR |
ADAPTER PROTEIN, PHOSPHOPROTEIN BINDING, PROTEIN BINDING-INHIBITOR complex |
01/30/2012 |
1.75 |
0.149 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DHR |
Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening |
PROTEIN BINDING/INHIBITOR |
ADAPTER PROTEIN, PHOSPHOPROTEIN BINDING, PROTEIN BINDING-INHIBITOR complex |
01/30/2012 |
1.4 |
0.1255 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DHU |
Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening |
PROTEIN BINDING/INHIBITOR |
HELICAL PROTEIN, ADAPTER PROTEIN, PHOSPHOPROTEIN BINDING, PROTEIN BINDING-INHIBITOR complex |
01/30/2012 |
1.67 |
0.131 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DL4 |
Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1). |
TRANSFERASE/DNA/INHIBITOR |
cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, TRANSFERASE-DNA-INHIBITOR complex |
02/05/2012 |
2.0 |
0.1943 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DL5 |
Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2). |
TRANSFERASE/DNA/INHIBITOR |
cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, TRANSFERASE-DNA-INHIBITOR complex |
02/05/2012 |
2.92 |
0.245 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DL6 |
Human DNA polymerase eta extending primer immediately after cisplatin crosslink (Pt-GG3). |
TRANSFERASE/DNA/INHIBITOR |
cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, TRANSFERASE-DNA-INHIBITOR complex |
02/05/2012 |
2.5 |
0.202 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DL2 |
Human DNA polymerase eta inserting dCMPNPP opposite CG template (GG0a) |
TRANSFERASE/DNA/INHIBITOR |
cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, TRANSFERASE-DNA-INHIBITOR complex |
02/05/2012 |
2.15 |
0.193 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DL3 |
Human DNA polymerase eta inserting dCMPNPP opposite GG template (GG0b). |
TRANSFERASE/DNA/INHIBITOR |
cisplatin, chemoresistence, translesion synthesis, human DNA polymerse eta, kinetics, molecular splint, inhibition, DNA distorsion, second TLS polymerase, nucleotidyl transfer reaction, PCNA, nucleus, TRANSFERASE-DNA-INHIBITOR complex |
02/05/2012 |
2.1 |
0.204 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
1 |
| 4DLV |
H-Ras Set 2 CaCl2/DTT, ordered off |
SIGNALING PROTEIN |
GTP-BINDING, NUCLEOTIDE BINDING, SIGNALING PROTEIN |
02/06/2012 |
1.57 |
0.1878 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 4DLX |
H-Ras Set 1 CaCl2/DTE, ordered off |
SIGNALING PROTEIN |
GTP-BINDING, NUCLEOTIDE BINDING, SIGNALING PROTEIN |
02/06/2012 |
1.73 |
0.1694 |
Homo sapiens |
Escherichia coli |
X-RAY DIFFRACTION |
2 |
| 2VDP |
Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV |
CELL ADHESION/IMMUNE SYSTEM |
CELL ADHESION-IMMUNE SYSTEM COMPLEX, FIBRINOGEN BINDING, PLATELET INTEGRIN ALPHAIIBBETA3, GLYCOPROTEIN, CELL ADHESION, MEMBRANE, INTEGRIN, RECEPTOR, ANTAGONIST, HOST-VIRUS INTERACTION, PYRROLIDONE CARBOXYLIC ACID, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, CLEAVAGE ON PAIR OF BASIC RESIDUES |
10/10/2007 |
2.8 |
0.156 |
MUS MUSCULUS |
CRICETULUS GRISEUS |
X-RAY DIFFRACTION |
1 |
| 2VDQ |
Integrin AlphaIIbBeta3 Headpiece Bound to a Chimeric Fibrinogen Gamma chain peptide, HHLGGAKQRGDV |
CELL ADHESION/IMMUNE SYSTEM |
CELL ADHESION-IMMUNE SYSTEM COMPLEX, FIBRINOGEN BINDING, PLATELET INTEGRIN ALPHAIIBBETA3, GLYCOPROTEIN, CELL ADHESION, MEMBRANE, INTEGRIN, RECEPTOR, ANTAGONIST, HOST-VIRUS INTERACTION, PYRROLIDONE CARBOXYLIC ACID, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, CLEAVAGE ON PAIR OF BASIC RESIDUES |
10/10/2007 |
2.6 |
0.141 |
MUS MUSCULUS |
CRICETULUS GRISEUS |
X-RAY DIFFRACTION |
1 |
| 2VDR |
Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV |
CELL ADHESION/IMMUNE SYSTEM |
CELL ADHESION-IMMUNE SYSTEM COMPLEX, FIBRINOGEN BINDING, PLATELET INTEGRIN ALPHAIIBBETA3, GLYCOPROTEIN, CELL ADHESION, MEMBRANE, INTEGRIN, RECEPTOR, ANTAGONIST, HOST-VIRUS INTERACTION, PYRROLIDONE CARBOXYLIC ACID, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, CLEAVAGE ON PAIR OF BASIC RESIDUES |
10/10/2007 |
2.4 |
0.148 |
MUS MUSCULUS |
CRICETULUS GRISEUS |
X-RAY DIFFRACTION |
1 |
| 2VDN |
Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Eptifibatide |
CELL ADHESION/IMMUNE SYSTEM |
CELL ADHESION-IMMUNE SYSTEM COMPLEX, FIBRINOGEN BINDING, PLATELET INTEGRIN ALPHAIIBBETA3, GLYCOPROTEIN, CELL ADHESION, MEMBRANE, INTEGRIN, RECEPTOR, ANTAGONIST, HOST-VIRUS INTERACTION, PYRROLIDONE CARBOXYLIC ACID, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, CLEAVAGE ON PAIR OF BASIC RESIDUES |
10/10/2007 |
2.9 |
0.163 |
MUS MUSCULUS |
CRICETULUS GRISEUS |
X-RAY DIFFRACTION |
1 |
| 2VDO |
Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide, HHLGGAKQAGDV |
CELL ADHESION/IMMUNE SYSTEM |
CELL ADHESION-IMMUNE SYSTEM COMPLEX, FIBRINOGEN BINDING, PLATELET INTEGRIN ALPHAIIBBETA3, GLYCOPROTEIN, CELL ADHESION, MEMBRANE, INTEGRIN, RECEPTOR, ANTAGONIST, HOST-VIRUS INTERACTION, PYRROLIDONE CARBOXYLIC ACID, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, CLEAVAGE ON PAIR OF BASIC RESIDUES |
10/10/2007 |
2.8 |
0.148 |
MUS MUSCULUS |
CRICETULUS GRISEUS |
X-RAY DIFFRACTION |
1 |
| 2W8K |
Y-family DNA polymerase Dpo4 bypassing N2-naphthyl-guanine adduct in syn orientation |
TRANSFERASE/DNA |
DNA-DIRECTED DNA POLYMERASE, DNA, DPO4, ADDUCT, N2-ALKYL, CYTOPLASM, MAGNESIUM, TRANSFERASE, METAL-BINDING, MUTATOR PROTEIN, DNA REPLICATION, NUCLEOTIDYLTRANSFERASE, COMPLEX, POLYMERASE, DNA DAMAGE, DNA REPAIR, DNA-BINDING, TRANSFERASE/DNA, TRANSFERASE-DNA complex |
01/16/2009 |
3.1 |
0.233 |
SULFOLOBUS SOLFATARICUS |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
1 |
| 2WAT |
Structure of the fungal type I FAS PPT domain in complex with CoA |
TRANSFERASE |
COA, FAS, PPT, NAD, NADP, TRANSFERASE, PHOSPHOPROTEIN, OXIDOREDUCTASE, LIPID SYNTHESIS, PHOSPHOPANTETHEINE TRANSFERASE, PHOSPHOPANTETHEINE, MULTIFUNCTIONAL ENZYME, FATTY ACID BIOSYNTHESIS, PHOSPHOPANTETHEINYLATION |
02/15/2009 |
2.2 |
0.217 |
SACCHAROMYCES CEREVISIAE |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |
| 2WDZ |
Crystal structure of the short chain dehydrogenase Galactitol- Dehydrogenase (GatDH) of Rhodobacter sphaeroides in complex with NAD+ and 1,2-Pentandiol |
OXIDOREDUCTASE |
OXIDOREDUCTASE, ROSSMANN FOLD |
03/27/2009 |
1.95 |
0.187 |
RHODOBACTER SPHAEROIDES |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |
| 2W35 |
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair |
HYDROLASE |
HYPOXANTHINE, ENDONUCLEASE, ENDONUCLEASEV, HYDROLASE, INOSINE, DNA DAMAGE, DNA REPAIR |
11/06/2008 |
2.15 |
0.259 |
THERMOTOGA MARITIMA |
ESCHERICHIA COLI |
X-RAY DIFFRACTION |
2 |